Evidence-based policy and practice initiatives focused on prevention continue to grow at the state and federal levels. Despite this growth, many are recognizing the limits of the current evidence-base to meet the changing needs of policymakers and practitioners. In particular, gross or insufficient evidence of program costeffectiveness and savings has led to poor quality estimates being used to guide public investment. In this context, there is a growing need to build capacity to rapidly respond to decision-maker needs for investing in prevention. This includes the capacity to develop robust projections of fiscal impact from preventive strategies. This talk will include findings from an integrative data analysis project to link early functioning with adult outcomes. Discussion of efforts to strengthen causal inference and monetize outcomes will be shared. How this work is being used to inform projections of prevention investments will be considered.

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