Publications

Co-use of alcohol and cannabis is prevalent and linked with heightened risk for substance-related harms. The current study investigated the role of substance-related pleasure as a reinforcing factor for co-use relative to alcohol or cannabis use. Specifically, we used data from a 21-day diary study of college students to examine day-level associations between co-use and self-reported substance-related pleasure (any, level of pleasure).

Participants were 237 college students (65 % female sex at birth, ages 18–24) who reported 1+ alcohol and cannabis co-use occasion. Participants completed daily surveys across 21 consecutive days about yesterday’s substance use and experiences of pleasure, yielding 2,086 daily surveys involving alcohol and/or cannabis use.

Multilevel models indicated that odds of substance-related pleasure were higher on days with co-use relative to days with single-substance use, and level of pleasure was higher on co-use days relative to cannabis but not alcohol use days. Pleasure may serve as a reinforcing property of co-use that may be related to continued use despite experience of negative consequences. Intensity of pleasure related to co-use appears to be largely driven by use of alcohol. However, given mixed findings concerning level of pleasure, individuals may report co-use increases feelings of pleasure but do not actually experience more pleasure. Pleasure may serve as a viable target in future prevention and intervention programming targeting co-use.

Highlights

• Odds of substance-related pleasure were higher on days with co-use of alcohol and cannabis relative to days with single-substance use.

• Level of pleasure was higher on co-use days relative to cannabis but not alcohol use days.

• Pleasure may be a reinforcing property of co-use that may be related to continued use despite experience of negative consequences.

Publication Type: Journal Article

Focus Area: Foundational Science