Sleep Problems and Adolescent Drug Use
Mechanisms Underlying the Relationship between Sleep Problems and Drug Use in Adolescence
Duration: 2013 -
Principal Investigator: Diana Fishbein
Partners: University of California at Irvine, RTI, Brown University
This prospective, longitudinal study is designed to elucidate mechanisms underlying the relationship between sleep problems and propensity to drug/alcohol use in adolescents, from age 10 through 20. Our integrative, temporal model theorizes that sleep problems will be significant predictors of drug/alcohol initiation and escalation of use in adolescents.
We propose further that this relationship can be explained at least in part by emotion dysregulation, as measured by tasks that recruit affective limbic structures and perturbations in neuroendocrine (cortisol) functioning. Level of cognitive functioning will moderate the relationship between sleep problems and drug use. Exposure to prolonged stress is expected to amplify the mediational relationship.
Finally, the model predicts that eventual drug use will exacerbate sleep problems and lead to further decrements in sleep, emotion regulation, and cognition, promoting an escalating pattern of use
Neurocognitive characteristics of early marijuana use initiation in adolescents: A signature mapping analysis
Fishbein, D., Novak, S. P., Ridenour, T. A., Thornburg, V., Hammond, J. C., & Brown, J. (2016). Neurocognitive characteristics of early marijuana use initiation in adolescents: A signature mapping analysis. Journal of Studies on Alcohol and Drugs, 77(3), 431-440. doi: 19371888